Protein Info for GFF6142 in Variovorax sp. SCN45

Annotation: 2-aminoethylphosphonate ABC transporter permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 transmembrane" amino acids 29 to 55 (27 residues), see Phobius details amino acids 86 to 107 (22 residues), see Phobius details amino acids 119 to 143 (25 residues), see Phobius details amino acids 164 to 187 (24 residues), see Phobius details amino acids 209 to 230 (22 residues), see Phobius details amino acids 260 to 284 (25 residues), see Phobius details amino acids 310 to 335 (26 residues), see Phobius details amino acids 365 to 387 (23 residues), see Phobius details amino acids 399 to 420 (22 residues), see Phobius details amino acids 432 to 450 (19 residues), see Phobius details amino acids 500 to 518 (19 residues), see Phobius details amino acids 538 to 560 (23 residues), see Phobius details TIGR03262: putative 2-aminoethylphosphonate ABC transporter, permease protein" amino acids 28 to 573 (546 residues), 810.6 bits, see alignment E=3.4e-248 PF00528: BPD_transp_1" amino acids 110 to 289 (180 residues), 33.3 bits, see alignment E=2e-12

Best Hits

KEGG orthology group: K02011, iron(III) transport system permease protein (inferred from 94% identity to vpe:Varpa_1733)

Predicted SEED Role

"Ferric iron ABC transporter, permease protein" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (577 amino acids)

>GFF6142 2-aminoethylphosphonate ABC transporter permease protein (Variovorax sp. SCN45)
MNTLARPLPARAAFNARPVMRWSRDETIARAILLVVMVMLFVFLIAPLLTILAHAVQDRE
GRFVGLTHFITYFQTPSLLRAAWNSIWVSAAVVMISVPTAFVFAYALTRSRMPMPLKAVF
RLIALIPLLAPSLLSAISFVQWFGNQGALKFLLGGVSIYGAPGIIMAEVYNTFPHALMIL
VTALSLADGRLYEAATALRTRPFRQFMTITLPSCKYGLISAATVVFTYVVSDFGAPKVIG
GNFNVLSVDVFKQVVGQHNFSIGAVVGMLLLVPSIISFVIDYVVRRKLKAQLTARSVPYS
PKRRKLADPLLMLFCTVVCGLLLATIGMAIYTSLISLWPYDLSLTLKHYHFVLVESDMAD
AYTNSLIVAIATAVAGSLIVFVGAYLIEKTRNLGLMRKGMHLMAVLSMAVPGLVLGLGYV
MFFNHPANPLNFLYQTMAILIISMVVHYYTSSHLTAVTALKQIDNEFEAVSASLKVPFFK
TFLRVTVPVCLPAILDIGRYFFVVSMASLSCAIFLYTPETILASVAIMHLDDAGDIGPAA
ALASLIVVTSTVVCIAYSLLTRVLLSRTQAWRNLSRS