Protein Info for GFF6140 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter Saci_1521

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 480 transmembrane" amino acids 20 to 46 (27 residues), see Phobius details amino acids 61 to 80 (20 residues), see Phobius details amino acids 92 to 109 (18 residues), see Phobius details amino acids 115 to 138 (24 residues), see Phobius details amino acids 150 to 172 (23 residues), see Phobius details amino acids 182 to 201 (20 residues), see Phobius details amino acids 275 to 298 (24 residues), see Phobius details amino acids 310 to 329 (20 residues), see Phobius details amino acids 341 to 364 (24 residues), see Phobius details amino acids 370 to 391 (22 residues), see Phobius details amino acids 403 to 427 (25 residues), see Phobius details amino acids 433 to 454 (22 residues), see Phobius details PF07690: MFS_1" amino acids 42 to 360 (319 residues), 119.5 bits, see alignment E=2.5e-38 amino acids 281 to 466 (186 residues), 45.7 bits, see alignment E=6.9e-16 PF00083: Sugar_tr" amino acids 60 to 449 (390 residues), 164.2 bits, see alignment E=7.9e-52

Best Hits

KEGG orthology group: None (inferred from 90% identity to vpe:Varpa_1731)

Predicted SEED Role

"Transporter, MFS superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (480 amino acids)

>GFF6140 Uncharacterized MFS-type transporter Saci_1521 (Variovorax sp. SCN45)
MTVLRSDIPARLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSIGAVLERSDTLGLTAG
EIGLSGSVYVAGAVIGALLFGRLTDRLGRKKLFLVTLVVYTVGTLATAFSPDFAFFALCR
FVTGLGIGGEYAAINSAIDELIPARVRGRVNLAINGSFWIGAGLGAGLSLVLLDPHVIGP
VWGWRAGFALGAVLAVAILLVRRDVPESPRWLIAHGRADEARRIVEQIEAEVSAQHGPLP
APQGHVVNYTDARQTSPSMREVARVLFKRYRQRSVVALALMVSQAFFYNAIFFTYALVLT
RFYGVPEASVALYIFPFALGNVLGPLLLGPLFDSLGRRKMIALTYVLAGVGLALTGWAFM
MGWLDARSQALCWSAVFFLASAAASSAYLTVSEVFPLEMRAMAIAIFYAVGMGAGGFAAP
LLFGLLIETGSRGAVMVGYGIGAVLVIVAGLLALRYAADAERKPLEEVAPPLAAEGDGER