Protein Info for PS417_00310 in Pseudomonas simiae WCS417

Annotation: cysteine synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 183 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details PF04442: CtaG_Cox11" amino acids 28 to 169 (142 residues), 164.9 bits, see alignment E=7e-53

Best Hits

Swiss-Prot: 34% identical to COXZ_SINFN: Cytochrome c oxidase assembly protein CtaG (ctaG) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K02258, cytochrome c oxidase subunit XI assembly protein (inferred from 96% identity to pfs:PFLU0060)

MetaCyc: 81% identical to cytochrome c oxidase assembly protein (Pseudomonas putida KT2440)

Predicted SEED Role

"Cytochrome oxidase biogenesis protein Cox11-CtaG, copper delivery to Cox1" in subsystem Biogenesis of cytochrome c oxidases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U852 at UniProt or InterPro

Protein Sequence (183 amino acids)

>PS417_00310 cysteine synthase (Pseudomonas simiae WCS417)
MAESLPTKRLVTRLLILVVAMFAFGFALVPIYDVMCKAFGINGKTAGQYEGEQIVDSSRQ
VRVQFLSTNAIDMVWDFYAKADEVVVNPGAVTEMLFVAHNPTDKPMTAQAVPSISPAEAA
MYFHKTECFCFTQQVLQPGQRIEMPVRFIVDRDMPKDVKHLTLAYTLFDITARQPPVAVH
SGG