Protein Info for GFF607 in Methylophilus sp. DMC18

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 transmembrane" amino acids 129 to 150 (22 residues), see Phobius details PF07730: HisKA_3" amino acids 375 to 440 (66 residues), 52.2 bits, see alignment E=7.3e-18 PF02518: HATPase_c" amino acids 484 to 570 (87 residues), 41.8 bits, see alignment E=1.4e-14

Best Hits

Predicted SEED Role

"Nitrate/nitrite sensor protein (EC 2.7.3.-)" in subsystem Nitrate and nitrite ammonification (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (577 amino acids)

>GFF607 hypothetical protein (Methylophilus sp. DMC18)
MQAGSLFLLDYTANNQNVIQHITKEQIFWQHFSDTAIGEAPEQLTEAILKADPHLRFDLG
KKVAQINSHDATQVNQLLQKLREAREKISDSHFQQASITSQRLTVQTLISSYEQLVALLL
QEVEAKQSVISLLQLLSIYLAISCLITIAFRARKLLVHRLDTLVSFAGQDAQNEQREQDE
DEFVKIERLVYETSARLEGFKAENEWFNQNSSERLRRLIRSQDFLHEFVESINNTLLSET
VLRKSLFSLEKALNILNVSLIFTENDLGISTERVLFSNHKPEKLSDAILEDLTTTNLVRF
CTNDNSPHGNGFQCIAVGFVTPTGALGVLQVEAELEHVFDETETQLIELTAHLLSMVMGF
QGREQEGRRLALLEERAAIARELHDSLAQSLSFMKIQISRLQSASNNQLETNEFRGIVNE
LRDGLNTAYRELRELLATFRVHMDVRGLNSAIQTAIDEFSQRSNLSISLDNRLINCRLTV
NEEFHILHVLREALSNVVRHANASRVEISLNFQSSGTIIVIVDDDGIGYTATEASGHYGQ
SIMQERAESLGGNVAVLRRKQGGTRVRLIFTPQLPQS