Protein Info for GFF6062 in Variovorax sp. SCN45

Annotation: Sodium-dependent phosphate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 553 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 47 to 67 (21 residues), see Phobius details amino acids 76 to 100 (25 residues), see Phobius details amino acids 104 to 121 (18 residues), see Phobius details amino acids 132 to 151 (20 residues), see Phobius details amino acids 172 to 197 (26 residues), see Phobius details amino acids 208 to 228 (21 residues), see Phobius details amino acids 243 to 263 (21 residues), see Phobius details amino acids 275 to 298 (24 residues), see Phobius details TIGR00704: Na/Pi-cotransporter II-related protein" amino acids 2 to 306 (305 residues), 254.6 bits, see alignment E=8.7e-80 PF02690: Na_Pi_cotrans" amino acids 13 to 147 (135 residues), 117.5 bits, see alignment E=4.6e-38 amino acids 157 to 282 (126 residues), 31.7 bits, see alignment E=1.4e-11 PF01895: PhoU" amino acids 343 to 422 (80 residues), 48.2 bits, see alignment E=1.2e-16 amino acids 446 to 528 (83 residues), 31.7 bits, see alignment E=1.6e-11

Best Hits

KEGG orthology group: K03324, phosphate:Na+ symporter (inferred from 95% identity to vpe:Varpa_1361)

Predicted SEED Role

"Sodium-dependent phosphate transporter" in subsystem Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (553 amino acids)

>GFF6062 Sodium-dependent phosphate transporter (Variovorax sp. SCN45)
MKHLLNLLAAVALLVWGTHLVRTGVLRVFGANLRKILVQSMRNRFTAALSGIGVTALVQS
STATSLMTSSFVGQGLVTLPAALAVMRGADVGTALISVLFSADLSWLSPMFIFVGVVLFI
TRSASVAGRVGRVLIGLGLMLLALQLVVEATEPLFSSPAVRALLASLNSDVLLEITIGAV
LAIVAYSSLAVVLLVAAMATSNVVPLDVALGLVLGANLGSGLLAVLTTAKSAVSVRQVTI
GNLLFKALGVAIVAPFIGLWIRYVQPELPNQAHGVVLFHLAFNIVISVGFIGLTQWVAKL
VTRLLPVPQQPAGTTRLHHLDPSALSTPSLAISNAAREALHQADIVETMLIGTLDVIRHN
DLRLAQELRQLDDTVDELYSAIKYYMTRISREALGEEESRRWTDIISFTINMEQIGDIIE
RVIIDIEDKKIKPQRNFSEAGMAEIVELHGRLIANLRLSMSVFLNGNVRDAQKLLEEKVR
FRDLERAYATTHLDRLSDRTTLSIETSSLHIDLISDLKRINSHICSIAYPILESAGALAP
SRLKEPQLSQAES