Protein Info for PS417_03065 in Pseudomonas simiae WCS417

Annotation: peptidase A24

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 149 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 30 to 49 (20 residues), see Phobius details amino acids 56 to 75 (20 residues), see Phobius details amino acids 92 to 112 (21 residues), see Phobius details amino acids 132 to 148 (17 residues), see Phobius details PF01478: Peptidase_A24" amino acids 6 to 109 (104 residues), 55.4 bits, see alignment E=3.8e-19

Best Hits

KEGG orthology group: K02278, prepilin peptidase CpaA [EC: 3.4.23.43] (inferred from 85% identity to pfs:PFLU0639)

Predicted SEED Role

"Flp pilus assembly protein CpaA"

Isozymes

Compare fitness of predicted isozymes for: 3.4.23.43

Use Curated BLAST to search for 3.4.23.43

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TZ88 at UniProt or InterPro

Protein Sequence (149 amino acids)

>PS417_03065 peptidase A24 (Pseudomonas simiae WCS417)
MIHGVVILVWLGLCALQDMRQRQIANGLTLGVALLALAYLVWNGATWLGAPASEGGWAFA
VALLLTLPGYALGRFGAGDVKLLAALALASTWDALLWSLIGAAVFQGGWVLIRQRLRARQ
HNGLTAASTKQPFAPFVLTGFALYWLWIH