Protein Info for GFF603 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Monooxygenase, flavin-binding family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 PF00743: FMO-like" amino acids 7 to 384 (378 residues), 212.7 bits, see alignment E=2.2e-66 PF07992: Pyr_redox_2" amino acids 8 to 208 (201 residues), 39.5 bits, see alignment E=1.2e-13 PF13738: Pyr_redox_3" amino acids 11 to 212 (202 residues), 67.3 bits, see alignment E=3.6e-22 PF13450: NAD_binding_8" amino acids 12 to 48 (37 residues), 22.4 bits, see alignment 3e-08 PF13434: Lys_Orn_oxgnase" amino acids 49 to 209 (161 residues), 44.7 bits, see alignment E=2.5e-15

Best Hits

KEGG orthology group: None (inferred from 76% identity to vpe:Varpa_4064)

Predicted SEED Role

"Monooxygenase, flavin-binding family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (437 amino acids)

>GFF603 Monooxygenase, flavin-binding family (Hydrogenophaga sp. GW460-11-11-14-LB1)
MTTPTEQQIALIGAGPSGLAGARCLQKHGIPFQGFEAHTDVGGLWNIHNPRSTVYQSAHL
ISSKRMTEFSEFPMPEHVADYPSHRELLDYFSAFADHFGLREHYRFGVRVLSAVPLSDAP
GTLWRVTTEDAQGRQTVADYKGVVVANGTLAEPNMPRFEGHFAGELLHTSAYKSADQFRG
KRVLIVGAGNSGCDIAVDAVHQARSVDISVRRGYYFVPKYVFGKPADTIGGKIRLPPWLK
QKIDSTILKWFTGDPVRFGFPQPTYKMYESHPVVNSLILYHIGHGDVGVRADIARFDGHT
VHFKDGRQGDYDLVLAATGYKLHYPFLDHALLNWQGMAPRLYLNIFAPRFDRLAVLGMVE
ASGLGWQGRYEQAELVARYFKGLDEGKAGATAFRTAKAGPPPDLSGGYKYLQLERMAYYV
NKDVYRDTVRKAAEALA