Protein Info for GFF5935 in Variovorax sp. SCN45

Annotation: VgrG protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 791 transmembrane" amino acids 772 to 790 (19 residues), see Phobius details TIGR03361: type VI secretion system Vgr family protein" amino acids 13 to 569 (557 residues), 479.7 bits, see alignment E=1.1e-147 TIGR01646: Rhs element Vgr protein" amino acids 22 to 551 (530 residues), 367.2 bits, see alignment E=1.6e-113 PF05954: Phage_GPD" amino acids 26 to 334 (309 residues), 235.1 bits, see alignment E=2.2e-73 PF04717: Phage_base_V" amino acids 433 to 501 (69 residues), 60.2 bits, see alignment E=4.1e-20 PF22178: Gp5_trimer_C" amino acids 515 to 625 (111 residues), 124.4 bits, see alignment E=5.1e-40 PF06715: Gp5_C" amino acids 574 to 597 (24 residues), 21.4 bits, see alignment (E = 4.1e-08)

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (791 amino acids)

>GFF5935 VgrG protein (Variovorax sp. SCN45)
MADNEFRIDSDSPAKDDLMFWRIVGHEALARPSAYELTVLSKNKAIDAKDILGRAFDVVI
EFKDADGGTHERHCQGHAVRFVRAGHVGRHYEYRITLRSWFWLLTKRTNSRILQEKKVLE
VLDAVFEDSPIKRFKKTRADNVIGTHNPRRYCVQHQESDYGFLSRLLEDEGIYYWFDAHG
APGTMHLSDASDIAHEKLPANDTLHHMATDASEARFNEVSRWVSGRQFGTGKHASRDSDF
KAIKKKLGADADASGEHELASLEMFEFPGGYFTGDEGESRAKLRGDELRARRDRHWALTP
WPDVAAGRGFKFEGDPDGTRNGEYIIAACTFVASHRGYEGVSASAASAARPVQAALAEVL
RDDAVNADTLQVLEDLIAATPALAAGQPGTSAFLLTVMPADRPFRAPRLTPRVTMPGPQT
AIVVGPKGDELHVDDHGRVKVHFHWDRYDESDEKSTCWVRVSQPWAGKGWGGYFAPRIGQ
EVIVDFLNGDPDRPIIMGRVYNDDQPIPFKSHTQSGFRTRSTPKGNAANFNEFRFEDDKG
KEQVYLHAERNLDVEVEADETRNVGHDRTKTVGHDEKVKIKNDRTEEVTGNETITIHGKR
ELTVDKDQYVTIKTNHSEEVTGWKSTWVTGNHRLSTSANHDQTVQGNETIDVSGTRSDTV
VGAVTQKVGPFTQTVTGAMTVTAAGPITFNAPAGFTVVAPGGTKIIDMSLEQFGGKIFEG
YGIKITANLANMALDNAKFALNGVNLASTGMKLDKAMFNLADKDCEIKKSEALIGAFPGV
ALTLAAVKIFL