Protein Info for GFF5856 in Variovorax sp. SCN45

Annotation: Outer membrane receptor proteins, likely involved in siderophore uptake

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 843 signal peptide" amino acids 1 to 43 (43 residues), see Phobius details PF07715: Plug" amino acids 168 to 268 (101 residues), 66.8 bits, see alignment E=2.2e-22 TIGR01783: TonB-dependent siderophore receptor" amino acids 172 to 823 (652 residues), 318.2 bits, see alignment E=6.3e-99 PF00593: TonB_dep_Rec_b-barrel" amino acids 362 to 806 (445 residues), 154.5 bits, see alignment E=8.7e-49

Best Hits

KEGG orthology group: None (inferred from 69% identity to dac:Daci_5892)

Predicted SEED Role

"TonB-dependent siderophore receptor" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (843 amino acids)

>GFF5856 Outer membrane receptor proteins, likely involved in siderophore uptake (Variovorax sp. SCN45)
MISRLPLSSTPRRSRTARAVQGALCALGMGAAGLAPLQQALAADATAAPAQARKSYKVPA
GPLGPALLDFAGQAGVNLSLDLAKTRGLGTPGLSGAFSVEEGFSRLLAGSGLRTRRLAGG
DFTLDAAPVPAPAPTPSPAASATEAPHSGAELAAVTVTARTQSDLMAPTRQVTVLEREEL
DSLRQGSDSVATLLSKVVPGMADSSHTITDFGQTLRGRNMLVLVDGIPLNTNRDSSRNLA
NINPADVDQIEVLRGSSAIYGSGAAGGIVSIRTRQPSGEARAETTITGVSPLSRIGSAGL
GGEVQHYISGGGQVFDYAVSLGARRVGGSYDARGDRIAPEPSQGDLFDSNIYSASAKIGY
RIDADQRLQFSASRYDAKQDTDYAPDPSVARLPAGSVAARPLKGLQLDKQNRVTNSLLGL
DYSHRDIAGSTLAAQLYYRDFFTRFAPFDARGVVARGSNVDQVMQNSRVFGGRLTVKTPF
GADRKTQLTWGADFNQERTDMPLDVFEPKLYDLSRGLSFSRTGTLIFMPPITTRTLGGFA
QLQHRFNDNWSVEGGARYDKASASFDSFTPLSQLRARNPAQVPGGSVDYGAWTYNAGVVY
NPTSRHDIYASYSQGFELPDIGLQVRNATPSFNIRGSDLQPVKTDTVELGWRGRFDNAAA
NLSVFQSQSALGAVQSSFNGLIMTRTKERIHGIEGAIDYAGGNDRWSAGGSFTWMKGREL
PQGGTRYQDMWGYRIPPLKLTAYVEYKPRGTWSHRLQMTSYASKDYRLGGVDGFGRRDTS
GYTTVDLVSRWKIDEKNNLVLGIENLFNRRYFPLYSQLLRNSNNTSRLPAAGAVLKVSYT
HRW