Protein Info for GFF5846 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 397 PF02515: CoA_transf_3" amino acids 6 to 374 (369 residues), 375.9 bits, see alignment E=1.2e-116

Best Hits

KEGG orthology group: None (inferred from 67% identity to axy:AXYL_03880)

Predicted SEED Role

"L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16)" (EC 2.8.3.16)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 2.8.3.16

Use Curated BLAST to search for 2.8.3.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (397 amino acids)

>GFF5846 L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSDGPLKGLRVLDIATIIAGPSAASLLADYGADVVKLELPAGDGARAFPPFKEGKPLWWK
VINRNKKFITLDLRKPEGVAVFRRLLPKFDVLVENFRPGTLDTWGLDRDTLWSIQPRLVI
LRVTGFGQTGPYRQRPGFARIFEAMGGLAYISGEANKEPMHAGYPIGDSIGGLFGAVGIL
AALWKRANDPQAPGEEIDLSLTESVLKLLEVLAIRYDQLGEVHERSGNVNQYSSPAGVFR
TADAHWVTLAGSTDALFANNCRAIGRPELLEHQDFRRNPDRVQNAEKVNAIFAEWFAAHT
LEHILSAFHAAHGTVAPIYSVDQIFADPQVQAREFLRRVPDEDFGHVRMQDVVPRFTRDP
CHVTSTAMALGRHNEDVYSDLGITGQELAALRAAGVV