Protein Info for GFF5823 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Nitrate/nitrite response regulator protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 230 PF00072: Response_reg" amino acids 12 to 122 (111 residues), 86 bits, see alignment E=2e-28 PF00196: GerE" amino acids 170 to 225 (56 residues), 75.5 bits, see alignment E=1.9e-25

Best Hits

KEGG orthology group: K07684, two-component system, NarL family, nitrate/nitrite response regulator NarL (inferred from 59% identity to tin:Tint_2474)

Predicted SEED Role

"Nitrate/nitrite response regulator protein" in subsystem Nitrate and nitrite ammonification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (230 amino acids)

>GFF5823 Nitrate/nitrite response regulator protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MTDTPARPIQLLVVDDHSLFRRGLMALLAQDLRFEVIGEAGDVGEALRCVARQRPDVILL
DNHLPGVLGVDAIPALREAAPGSRVLMLTVSENEADLVAALKAGADGYLLKTVESHHLCE
AIVKVMEGESVVSPEMTTKLVSALRAQPTVNGNGEGGGATVATADAELASLSVRELEILH
LIARGDSNKLIARQLDIAETTVKIHVQHILRKLNLTSRVQAAVFAARHAS