Protein Info for GFF5812 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Cytochrome c oxidase subunit CcoN (EC 1.9.3.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 93 to 117 (25 residues), see Phobius details amino acids 143 to 163 (21 residues), see Phobius details amino acids 175 to 198 (24 residues), see Phobius details amino acids 210 to 232 (23 residues), see Phobius details amino acids 240 to 259 (20 residues), see Phobius details amino acids 278 to 299 (22 residues), see Phobius details amino acids 310 to 327 (18 residues), see Phobius details amino acids 339 to 361 (23 residues), see Phobius details amino acids 379 to 399 (21 residues), see Phobius details amino acids 419 to 438 (20 residues), see Phobius details amino acids 456 to 478 (23 residues), see Phobius details amino acids 504 to 525 (22 residues), see Phobius details PF00115: COX1" amino acids 96 to 508 (413 residues), 281.2 bits, see alignment E=7.9e-88

Best Hits

KEGG orthology group: K00404, cb-type cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 82% identity to rfr:Rfer_4127)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoN (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (550 amino acids)

>GFF5812 Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MDSAILSLLGAFLLSIIGLFIFIWSMRSGLLVENSKAASVIFARGEIGKVDDPALGDAAR
ESMQAAATQSGIEPHAADPDEMHARLEADTSTAFPVFMFIAFACAWLLLGSVAGLVSSIK
LHEPDWLVSEAWMTFGRLRSVHLNAVLYGWITNAALGMILWLLPRLLRTRLLGGIWAMLG
GALINTGIAGGVGAIAVGWTDGMEYLEIPWQIGIFIFLGFALVILPVLFTLVNRKVEHMY
VSVWYMVAALLWIALLYLVGKMPGVHTGVQQATTNWWYGHNVLGLWFTPVSVGAIYYFLP
KIIGRPVRSYNVSILGFWTLAFFYGQVGGHHLVGGPVPGWLVTLSIVQSMMMIIPVIAFT
INMALTMQGRMHLARYSPTLRFMMFGGLMYMLSSLQGSFEALRSVNQITHFTHFTVAHAH
LGAYAFVTMVLFGAIYFMMPRVLNWEWPYPRLISLHFWLAAIGASIYFVGLSIGGWLQGL
AMLDAARPFMDSVTLTYPYLKWRSVGGALMVASHVVFVGHFLAMALRFGPTRAGAALFWQ
QGQQELSHGK