Protein Info for GFF580 in Variovorax sp. SCN45

Annotation: Rhodanese domain protein UPF0176, Betaproteobacterial subgroup

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 PF17773: UPF0176_N" amino acids 6 to 95 (90 residues), 96.8 bits, see alignment E=8.3e-32 PF00581: Rhodanese" amino acids 121 to 214 (94 residues), 32.6 bits, see alignment E=9.5e-12

Best Hits

Swiss-Prot: 92% identical to Y3119_VARPS: UPF0176 protein Vapar_3119 (Vapar_3119) from Variovorax paradoxus (strain S110)

KEGG orthology group: K07146, UPF0176 protein (inferred from 92% identity to vap:Vapar_3119)

Predicted SEED Role

"Rhodanese domain protein UPF0176, Betaproteobacterial subgroup"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (263 amino acids)

>GFF580 Rhodanese domain protein UPF0176, Betaproteobacterial subgroup (Variovorax sp. SCN45)
VQEILNIAAYKFVAIDDSPELREDLRARAQALDLMGTILLAPEGINLFLAGSADGVRTFL
ADLRADARFADLEAKESWSATQPFRRMLVKLKREIIRMDHPAIQPAAGRAPGVDAPTLKR
WLDQGHDDEGREIALLDTRNDFEVDEGTFDGAIDWRITKFTEFPPALKEHRADFAGKTVV
SFCTGGIRCEKAAILMREEGIENVLQLEGGILKYFEQVGGAHYHGDCFVFDGRRALAPDL
SARAADASARAAEDIDLNLGLKT