Protein Info for GFF5791 in Variovorax sp. SCN45

Annotation: FIG00031715: Predicted metal-dependent phosphoesterases (PHP family)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 PF02811: PHP" amino acids 8 to 73 (66 residues), 42.6 bits, see alignment E=4.3e-15

Best Hits

Swiss-Prot: 54% identical to 35NBP_CHRVO: 3',5'-nucleoside bisphosphate phosphatase (CV_1693) from Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)

KEGG orthology group: K07053, (no description) (inferred from 96% identity to vap:Vapar_4021)

Predicted SEED Role

"COG0613, Predicted metal-dependent phosphoesterases (PHP family)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (285 amino acids)

>GFF5791 FIG00031715: Predicted metal-dependent phosphoesterases (PHP family) (Variovorax sp. SCN45)
VSSILNADLHCHSVVSDGTLTPEELAARAAANGVELWALTDHDEIGGQHRAAAAARANGM
RYLTGTEISVTFAGETVHIVGLGFDADDAAISQGLYDTRGGRGKRAQEMSEGLAKVGIHG
AYEGALKFVGNPELISRTHFARFLVEQGHCRDTPEVFRKFLTEGKPGYVPHRWASLKDAV
HWITAAKGMAVIAHPGRYKFSANEEYALFLEFKAHGGQAIEVVTGSHTPAEYVEYADKAL
EFDFAASRGSDFHSPDESHCDLGKLPPLPGALTPVWELLGHRIQQ