Protein Info for GFF5749 in Variovorax sp. SCN45

Annotation: Flagellar motor switch protein FliG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 332 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF14842: FliG_N" amino acids 6 to 103 (98 residues), 98.3 bits, see alignment E=7.7e-32 TIGR00207: flagellar motor switch protein FliG" amino acids 6 to 331 (326 residues), 376.1 bits, see alignment E=9.3e-117 PF14841: FliG_M" amino acids 117 to 187 (71 residues), 79.6 bits, see alignment E=3.3e-26 PF01706: FliG_C" amino acids 218 to 323 (106 residues), 138.5 bits, see alignment E=2.1e-44

Best Hits

Swiss-Prot: 58% identical to FLIG_SALTY: Flagellar motor switch protein FliG (fliG) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K02410, flagellar motor switch protein FliG (inferred from 84% identity to vap:Vapar_4169)

Predicted SEED Role

"Flagellar motor switch protein FliG" in subsystem Bacterial Chemotaxis or Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (332 amino acids)

>GFF5749 Flagellar motor switch protein FliG (Variovorax sp. SCN45)
MSSELGTRKSAILLMALGEDRAAAALHQLPTSEVQALGLAMSKLTSVSKEELAAVLAEFR
EETEQLSALHLGSTSYIRAVLKKALGDDRASNLLEDILQPDEPRGGIERLNELEAGEVAE
LIRDEHPQILATLVVHLDRMKASEVLEKLPTRLRHDVIMRVATLGGVQPSALKELTDVLT
EMLAGQGVRRNRLGGVRTAAEIVNLMSTAVEEEAIAHVREKDEALAQRIVDEMFVFENLL
GLEDRSIQRLLKDIESDSLIIALKGAPMELRDKFLNNMSQRAAETLREDMELRGPVRVSQ
VETEQKAILQVARRLAEAGEIVIAAPGTDDFV