Protein Info for GFF5734 in Variovorax sp. SCN45

Annotation: Methyl-accepting chemotaxis sensor/transducer protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 576 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 190 to 210 (21 residues), see Phobius details PF02203: TarH" amino acids 3 to 173 (171 residues), 39.4 bits, see alignment E=1.2e-13 PF12729: 4HB_MCP_1" amino acids 5 to 172 (168 residues), 71.9 bits, see alignment E=1e-23 PF00672: HAMP" amino acids 212 to 255 (44 residues), 41 bits, see alignment 4e-14 PF00015: MCPsignal" amino acids 324 to 479 (156 residues), 190.8 bits, see alignment E=3.6e-60

Best Hits

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 66% identity to vap:Vapar_4189)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (576 amino acids)

>GFF5734 Methyl-accepting chemotaxis sensor/transducer protein (Variovorax sp. SCN45)
MNLKNLKIGTRLGFGFAVVLLLMAVIAATGMLRLGKVGKATEEVMERALVKERLANQWSN
LLGPAIVNSFAMVKATDPKVAAYFEKGRAEKSAQINPVQKKLEELLTSPEEKKLYANVAD
ARAIVLQSIGQINKLKSEGKNEEAMDMADNKFAPALAVNEEAVAKLAAYQRDRIDELAKG
IEADHSSGETLLLALSGIALLLGALFSWRLTLGIVRPLGQAVQVAETVAAGDLSTNIKVE
SRDEAGQLMQALKNMNESLAKVVGEVRTGTETIATASGQIASGNQDLSSRTEEQASSLEQ
TAASMEELTSTVKQNADNARQANQLAMSASEVAVKGGSVVSQVVDTMGSINASSKKIVDI
IGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSAAAAKEIKTLIGNS
VEKVEEGSKQVEEAGRTMDEIVGSVKRVTDIMGEITAASQEQTSGIEQINQAITQMDQAT
QQNAALVEEASAAAQSLQEQAGSLVQAVSVFKLDANAVATVRPGFTRITPIPKTARPAPA
AAKRPAKALPARREPGGAAAPQLAMAGDAKGDWTEF