Protein Info for GFF5733 in Variovorax sp. SCN45

Annotation: Methyl-accepting chemotaxis sensor/transducer protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 544 transmembrane" amino acids 159 to 180 (22 residues), see Phobius details PF12729: 4HB_MCP_1" amino acids 1 to 154 (154 residues), 73.8 bits, see alignment E=2e-24 PF00672: HAMP" amino acids 178 to 224 (47 residues), 37.6 bits, see alignment 3.4e-13 PF00015: MCPsignal" amino acids 293 to 449 (157 residues), 190.1 bits, see alignment E=4.5e-60

Best Hits

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 62% identity to ctt:CtCNB1_2983)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (544 amino acids)

>GFF5733 Methyl-accepting chemotaxis sensor/transducer protein (Variovorax sp. SCN45)
MQLGKVHDMSTDLATNWMPATRSLLEMKNLMSRYRTQELQHILAGSYDEMAVYEKAMDET
WANLQKNRAEYEKLISEPEEREIYPTLQKLLTEYSLEHNKIVAISHTQENEQATALIRGK
SLQLSRDINGALDKLTEVNVAGAIRAGETADTVYGEARLWVLGLLLGSVALGLVLALWIA
RIVSRPLSEAVKVAQSVAAGDLTSHIEARTTDETGLLLEALKGMNDSLAKIVGEVRIGTD
TIATASSQIASGNQDLSSRTEEQASSLEQTAASMEELTSTVKQNADNARQANQLAVSASE
VAVKGGSVVSQVVDTMGSINASSKKIVDIIGVIDGIAFQTNILALNAAVEAARAGEQGRG
FAVVASEVRSLAQRSAAAAKEIKTLIGDSVEKVEEGSKQVAEAGRTMDEIVGSVRRVTDI
MGEITAASQEQTSGIEQINQAITQMDQVTQQNAALVEEASAAAQSLQEQAGSLVQSVSIF
KLDANALATRASFTRLTPIPRAAAAVKPAPKRPAKALPARREPGSGPAPQLAMAGDAKGD
WTEF