Protein Info for GFF5729 in Variovorax sp. SCN45

Annotation: Methyl-accepting chemotaxis sensor/transducer protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 534 transmembrane" amino acids 169 to 189 (21 residues), see Phobius details amino acids 202 to 222 (21 residues), see Phobius details PF13426: PAS_9" amino acids 19 to 110 (92 residues), 41.5 bits, see alignment E=4.2e-14 PF00989: PAS" amino acids 24 to 111 (88 residues), 39.4 bits, see alignment E=1.7e-13 PF08448: PAS_4" amino acids 24 to 112 (89 residues), 30.1 bits, see alignment E=1.4e-10 TIGR00229: PAS domain S-box protein" amino acids 24 to 114 (91 residues), 51.5 bits, see alignment E=5.5e-18 PF08447: PAS_3" amino acids 31 to 113 (83 residues), 54.1 bits, see alignment E=4.8e-18 PF00672: HAMP" amino acids 225 to 274 (50 residues), 36.7 bits, see alignment 1.3e-12 PF00015: MCPsignal" amino acids 339 to 495 (157 residues), 187.4 bits, see alignment E=6.1e-59

Best Hits

KEGG orthology group: K03776, aerotaxis receptor (inferred from 62% identity to tbd:Tbd_2406)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (534 amino acids)

>GFF5729 Methyl-accepting chemotaxis sensor/transducer protein (Variovorax sp. SCN45)
MRVNLPVTGIEYELPRDAALVSRTDLKGRITYVNPAFVEASGYAVDELMGKAHNIVRHPD
VPPEAFADLWQTLGQGLPWTGIIKNRRSNGDFYWVLANVTPIRRDGRVQGYMSVRSRPDR
ADVAEADALYRRLREGGAKGVTLQQGQVVQRGWMNPLAQLRRIPVRQRVFGATTAAALLT
LGLGIAGWMEAGRLVASAGVHSWLPGALAAGGVGFALAWLGLGQFLGRTVFRPLDEALHV
ARAIAGGDLAKFEIRRGDEITGLLRALNQMSANLFAIVADVGTNVAGVMSASSQIASGNQ
DLSSRTEQQASSLEQTAASMEELTSTVKQNADNARQANQLAVSASEVAVKGGSVVSQVVD
TMGSINASSRKIVDIIGVIDGIAFQTNILALNAAVEAARAGEQGKGFAVVASEVRSLAQR
SAAAAKEIKTLIGDSVEKVEAGSKQVAEAGRTMEEIVGSVRRVTDIMGEITTASQEQTSG
IEQINQAIAQMDQVTQQNAALVEEASATAQSLQEQADGLVRAVRVFRAEAAEIH