Protein Info for GFF57 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Permeases of the major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 transmembrane" amino acids 27 to 44 (18 residues), see Phobius details amino acids 53 to 74 (22 residues), see Phobius details amino acids 86 to 107 (22 residues), see Phobius details amino acids 115 to 140 (26 residues), see Phobius details amino acids 153 to 174 (22 residues), see Phobius details amino acids 184 to 203 (20 residues), see Phobius details amino acids 244 to 268 (25 residues), see Phobius details amino acids 275 to 298 (24 residues), see Phobius details amino acids 310 to 329 (20 residues), see Phobius details amino acids 335 to 355 (21 residues), see Phobius details amino acids 375 to 395 (21 residues), see Phobius details amino acids 403 to 424 (22 residues), see Phobius details PF00083: Sugar_tr" amino acids 16 to 428 (413 residues), 83.7 bits, see alignment E=1.4e-27 PF07690: MFS_1" amino acids 46 to 380 (335 residues), 79.4 bits, see alignment E=2.5e-26

Best Hits

KEGG orthology group: None (inferred from 99% identity to sei:SPC_0228)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (433 amino acids)

>GFF57 Permeases of the major facilitator superfamily (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MSGTYNATIRRVVVSAWIGNSIEYYDFLLYGLASALVFGPLFFPGASPLTATLSSFASFG
VGFISRPLGALFFGNRGDTLGRKNTLLITLGGMGAVTFLIGCLPSYASIGALAPALLVIL
RFLQGFMVGGEWGGAMLMVVEYAAGKHRGRLSALSQTGGLTGQLLATGVFIVVTQLPQEA
LLSWGWRIPFLLSALLVLPGLYMRHRLDETPVFRAFKKQQAINHRQQREERPVVKVVREQ
WRSILLIIILRFAESVPFFLATVFAVSWATTQLGIASLTILYIVMFTCLLAYPMHVLFGI
MSDRRGCRQVYIFGALFVAAMAFPFFWLLESRSLILMTMGYVLLINIGHNSLNAVQPSFF
AGLFHPPVRYSGSSIGAQLGAVVAGGFTPFIAKALSAVYDNSWALVAGYVVLTALASAFA
AKIAPETVLPHSP