Protein Info for GFF568 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Cell division protein FtsZ (EC 3.4.24.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 402 TIGR00065: cell division protein FtsZ" amino acids 9 to 321 (313 residues), 373.7 bits, see alignment E=5.3e-116 PF00091: Tubulin" amino acids 16 to 173 (158 residues), 152.8 bits, see alignment E=1.4e-48 PF12327: FtsZ_C" amino acids 222 to 317 (96 residues), 93.3 bits, see alignment E=9.6e-31

Best Hits

Swiss-Prot: 55% identical to FTSZ_COXBU: Cell division protein FtsZ (ftsZ) from Coxiella burnetii (strain RSA 493 / Nine Mile phase I)

KEGG orthology group: K03531, cell division protein FtsZ (inferred from 90% identity to pol:Bpro_1080)

Predicted SEED Role

"Cell division protein FtsZ (EC 3.4.24.-)" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (402 amino acids)

>GFF568 Cell division protein FtsZ (EC 3.4.24.-) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSIEMIEVEEFNQGTQIKVIGVGGGGGNAVEHMISRSVQGVEFICANTDAQSLSRSAAHK
TIQLGTSGLGAGSKPEKGRDAAEVAVDDIREAIAGAHMLFITAGMGGGTGTGAAPVIARV
AKEMGILTVGVVTKPFDWEGGRRMTNADSGLAELEANVDSLIVVLNEKLLEVLGDDVTQD
EAFAHANDVLKNAVGGIAEIINEYGNVNVDFEDVRTVMGEPGKAMMGTAVAAGPDRARIA
AEQAVACPLLEGIDLSGAKGVLVLVTAAKGSLKLSESKLAMNTIRAYASPEAHVIYGAAY
DDALGDEMRVTVVATGLSRQGVRRTAPPLQVLRTGTDNVPFNVPTVNAAVGGPGAAQPDY
NSMAVPSVWRTNRTQAAAKVDALASGGMDDFEIPAFLRKQAD