Protein Info for GFF5679 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 transmembrane" amino acids 51 to 69 (19 residues), see Phobius details amino acids 75 to 99 (25 residues), see Phobius details amino acids 110 to 129 (20 residues), see Phobius details amino acids 134 to 155 (22 residues), see Phobius details amino acids 174 to 198 (25 residues), see Phobius details amino acids 211 to 232 (22 residues), see Phobius details amino acids 263 to 288 (26 residues), see Phobius details amino acids 300 to 321 (22 residues), see Phobius details amino acids 328 to 346 (19 residues), see Phobius details amino acids 357 to 377 (21 residues), see Phobius details amino acids 388 to 411 (24 residues), see Phobius details amino acids 418 to 438 (21 residues), see Phobius details PF00083: Sugar_tr" amino acids 40 to 232 (193 residues), 51.3 bits, see alignment E=8.9e-18 PF07690: MFS_1" amino acids 135 to 406 (272 residues), 60.7 bits, see alignment E=1.2e-20

Best Hits

KEGG orthology group: None (inferred from 88% identity to vap:Vapar_4045)

Predicted SEED Role

"MFS permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (445 amino acids)

>GFF5679 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MTTSSISPQGAHPLPNSPETGARQGDDHSHIAPGEIAVGVIIGRASEYFDFFVYGIASVL
VFPAVFFPFEQHLEGVLYSFLIFSFAFIARPFGTVISMAIQRRFGREAKLTLALFVLGTS
TAGIAFLPGYASLGFTAIVLLSVFRFGQGLALGGSWDGLPSLLALNAPANRRGWYAMLGQ
LGAPIGFFIASALFAYLYSSLPSEDFLDWGWRYSFYVAFAINVVALFARLRLVATDEYSR
LLEERELEPTSVTELVGSQGSNILIGAFAALASYALFHLITVFPLSWITLYSDQSVTEFL
VVQMVGAVLGAAGIVASGLLADRIGRRFTLGGLAAVIAAFSGFAPTLLDGGRIGQDIFIL
VGFVILGLSYGQAAGAVTSNFAPKYRYVGAALTADVAWLIGAAFAPLVALGLSAHFGLAY
VSVYLLSGAVATLAALGLNRALARD