Protein Info for GFF5650 in Variovorax sp. SCN45

Annotation: Selenocysteine-specific translation elongation factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 635 TIGR00475: selenocysteine-specific translation elongation factor" amino acids 1 to 625 (625 residues), 480.2 bits, see alignment E=5.1e-148 PF00009: GTP_EFTU" amino acids 2 to 168 (167 residues), 112.2 bits, see alignment E=5.9e-36 PF03144: GTP_EFTU_D2" amino acids 195 to 262 (68 residues), 57 bits, see alignment E=5.2e-19 PF09106: SelB-wing_2" amino acids 442 to 496 (55 residues), 53 bits, see alignment 7.8e-18 PF21214: bact_SelB_WH_2nd" amino acids 506 to 564 (59 residues), 35 bits, see alignment 2.7e-12 PF09107: SelB-wing_3" amino acids 584 to 624 (41 residues), 57 bits, see alignment 2.8e-19

Best Hits

KEGG orthology group: K03833, selenocysteine-specific elongation factor (inferred from 55% identity to bte:BTH_II0712)

Predicted SEED Role

"Selenocysteine-specific translation elongation factor" in subsystem Selenocysteine metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (635 amino acids)

>GFF5650 Selenocysteine-specific translation elongation factor (Variovorax sp. SCN45)
MIIGTAGHIDHGKTTLVRALTGVDTDRLPEEKRRGISIELGYAYLHAPDGVSLGFVDVPG
HERLLHTMLAGATGIDHALLVVAADDGVMPQTREHLAVVALLGVREATVAITKIDRIDES
MREARLAEVRSDIAALLAPTPLAGAPMLAVSATTGEGVDTLRERLLDVASKARAREDDLA
FRLAVDRAFTLSGVGTVVTGTVFSGTVRIGDELRVVPGDRSVRVRGIHAQNQKAESAHAG
QRCALALAGVTKDEMHRGDWVCAPAIALATDRIDVLLTLWPDEAKPLRSGTTVHAHLGAS
DVMASLALLDRDALAPGETALAQLVTKESVGAWHGDRGVLRDASATRTMAGVRVLDPFAP
VRYRRLPERLRTLAGWAIDDRAARVAALLHNAPLGIDTARLARALSLPDEAALPLPADAV
RIEHTAIAQRHLDALDAQITGRLADFHHDAPDEVGPDARRLRRLAAPRTDDALWRHALDA
LVARGALVRSGTWLHLPDHAARLGEAEQKLAQKLLPRLADGGFDPPWVRDLAKDCSASEP
MVRQTLASLARRGEAFQVVKDLYYPLATIERLAAIARDCLDGPEGLQAASFRDATGLGRK
RAIQLLEFFDRVGLTRRVKDAHLLRPDTSLFGARP