Protein Info for GFF5639 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 291 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 39 to 56 (18 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details amino acids 90 to 113 (24 residues), see Phobius details amino acids 136 to 160 (25 residues), see Phobius details amino acids 191 to 216 (26 residues), see Phobius details amino acids 225 to 258 (34 residues), see Phobius details amino acids 265 to 284 (20 residues), see Phobius details PF02653: BPD_transp_2" amino acids 7 to 275 (269 residues), 118.8 bits, see alignment E=1.3e-38

Best Hits

KEGG orthology group: K01997, branched-chain amino acid transport system permease protein (inferred from 72% identity to vap:Vapar_4940)

Predicted SEED Role

"High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (291 amino acids)

>GFF5639 High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1) (Hydrogenophaga sp. GW460-11-11-14-LB1)
LLILQILVAGIALGCVYGLIALGFVLIYKATETVNFAQGELMMLGAFICLACMGPLGMPF
WLAAVAAVAAMALVGLGLERAVIRPVLGQPAFSIVMLTIGVGYVARGGVTMIPGIGTDTH
TLAAPYKGEAVELSGLVLAGEQVLIIAATAALCAGLWLLFRFTRVGIAMQASSQNQLAAY
YMGIPVQKLNGLVWALAAAVATVAGILLAPITFVHVNMGFIGLKAFPAAIIGGFSSLPGA
IVGGLVIGVVEALSGFFLPEGFKDVMPYVVVLIMLAVRPTGLFGERARKKV