Protein Info for GFF5626 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Tricarboxylate transport protein TctC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF03401: TctC" amino acids 48 to 317 (270 residues), 253.2 bits, see alignment E=1.3e-79

Best Hits

KEGG orthology group: None (inferred from 48% identity to cti:RALTA_B0411)

Predicted SEED Role

"Tricarboxylate transport protein TctC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (321 amino acids)

>GFF5626 Tricarboxylate transport protein TctC (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSKIFRAALAACAAALTLAPVAAQTAYPTRTVRIIVPAPAGTGPDVLARLYAQHLGQALG
QPFVVDNRPGASGNLGAEAVAKAPADGYTLLYGYNQIFTMNPHLFTKLAYDSAKDLAPVT
QTVGTAYVLAGNNNLPAQDLAGVIDYARKNPGKLAYASYGPGTASHLIMELIQDSEKIQL
LHVPYKQGQMTDVINGQVAMVIEPFPSGIPMAKSGRVKALAVTGEKRIAELPNVPAMNEA
VRGLNLLGWQGIWTTAGTPPEVITRLNAEFVRITKLPDMQKRIQDFASVPIGSSPQEMAA
VIQRESRQWGAVIRDKHIVLD