Protein Info for GFF562 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Cell division protein FtsW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 transmembrane" amino acids 75 to 97 (23 residues), see Phobius details amino acids 111 to 134 (24 residues), see Phobius details amino acids 141 to 161 (21 residues), see Phobius details amino acids 180 to 193 (14 residues), see Phobius details amino acids 206 to 225 (20 residues), see Phobius details amino acids 231 to 248 (18 residues), see Phobius details amino acids 254 to 272 (19 residues), see Phobius details amino acids 332 to 356 (25 residues), see Phobius details amino acids 368 to 392 (25 residues), see Phobius details amino acids 410 to 431 (22 residues), see Phobius details TIGR02614: cell division protein FtsW" amino acids 73 to 434 (362 residues), 393.2 bits, see alignment E=5.7e-122 PF01098: FTSW_RODA_SPOVE" amino acids 75 to 436 (362 residues), 343.4 bits, see alignment E=7.5e-107

Best Hits

Swiss-Prot: 74% identical to FTSW_VARPE: Probable peptidoglycan glycosyltransferase FtsW (ftsW) from Variovorax paradoxus (strain EPS)

KEGG orthology group: K03588, cell division protein FtsW (inferred from 77% identity to pol:Bpro_1074)

Predicted SEED Role

"Cell division protein FtsW" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (444 amino acids)

>GFF562 Cell division protein FtsW (Hydrogenophaga sp. GW460-11-11-14-LB1)
VKKKTVAAAKANSAPWGQRVRAALTGLLPRFPGRDLAGALAGGSSRDDLPVRLSNRTYAG
TRNVAVRELGFDQPLLWVVVALLAWGLVMVYSASIALPDNPRFQNYAHTHFVLRHGISMV
IGVIAAMVAFQLPLRSWEKMAPWLFAVALVLLALVLLPFIGRGVNGARRWISLGIMNFQP
SELAKLAVLLYAASYMVRKMEVKERFFHAVAPMAVAVGVVGMLLLAEPDMGAFMVIVVIA
MGILFLGGVNARMFFLMALVVVGAFALMVMTSEFRRQRVFAYLDPWSVEHALGKGYQLSH
SLIAFGRGEIFGVGLGGSVEKLHWLPEAHTDFLLAVIGEEFGLLGVVVLIALFLWLTRRI
MHIGRQAIALDQVFAGLVAQGVGLWMGFQAFINIGVNLGALPTKGLTLPLMSYGGSAILL
NLVAIALVLRVDYENRQMMKGGRA