Protein Info for GFF5607 in Variovorax sp. SCN45

Annotation: Sigma-54 activated regulatory protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 PF01590: GAF" amino acids 88 to 224 (137 residues), 33.3 bits, see alignment E=6.7e-12 PF02954: HTH_8" amino acids 377 to 415 (39 residues), 46.5 bits, see alignment 2.4e-16

Best Hits

KEGG orthology group: None (inferred from 83% identity to vpe:Varpa_5730)

Predicted SEED Role

"Sigma-54 activated regulatory protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (426 amino acids)

>GFF5607 Sigma-54 activated regulatory protein (Variovorax sp. SCN45)
MSPGKFDSRLGTADAPRQLFASTPAQRVALARRQFFEEGVRPSGLVGEAVIQSWLRCSRT
HADRQRIVPFDAVTPSRLHATLARNRELLEVARQELAQMENMLAGTDCRVILTDRDGVVV
HVSDQPAAAHQPVLRKTARVGVNISERVVGTTAPGIVASTGQACTVDGAEHYFDVLGHMQ
CAAAPIRDVTGRLAGVLDLTAEARRFGFDAASMVALYATAIENRLLQAQSSDHLILRFQA
SPTLLGTPLEALAGIAPDGTIAWLNNAGSRLLGRLPEAADERDVECLLGHDLASLMRLGR
REAAQPLRLASGLGVWVQARLRGPDGADFRHAVAMPGEAAPVAIERDAVAAIATAVGTTE
GPADTDTGEAASPAGTLREHSRKLIEDTLAAHGGNVSQAARQLRVSRGTLYRRLRGWCDD
AAPTDD