Protein Info for GFF5594 in Variovorax sp. SCN45

Annotation: Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 358 PF00005: ABC_tran" amino acids 20 to 161 (142 residues), 127 bits, see alignment E=8.5e-41 PF08402: TOBE_2" amino acids 274 to 351 (78 residues), 50 bits, see alignment E=2.7e-17

Best Hits

KEGG orthology group: K02052, putative spermidine/putrescine transport system ATP-binding protein (inferred from 61% identity to met:M446_4680)

Predicted SEED Role

"Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1)" in subsystem Polyamine Metabolism (TC 3.A.1.11.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (358 amino acids)

>GFF5594 Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1) (Variovorax sp. SCN45)
VSYLRLDNLQCTYDRTVAVRNLNLDVAQGELLALLGPSGCGKSTTLRMVAGFVQPSAGRI
FFGEREVTHAPPHARDTGMVFQGYALFMHMSVAENVAFGLQMRKVPRAEQAARVKEALRL
VRLDHLADRRPAALSGGQQQRVALARALVVQPAVFLLDEPMSNLDARLRTEVRLEIRALQ
QRLGLTTLLVTHDQEEALTTADRLAVMDHGRVRQVGTPRQVYEQPVDQFVANFIGRCNLV
PGRLDAPGVFRAGAHALPCAPFEGLQSTKNDLALMVRPDRIRIANAGEQGLPARVRLSTY
LGGTTEWNFETDVGPIAVAQPSTLAHGTGARGPAEGERVSLQWSPEHALALPADATSA