Protein Info for GFF5553 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Large protein containing transglutaminase-like domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1168 PF08379: Bact_transglu_N" amino acids 6 to 84 (79 residues), 87.6 bits, see alignment 1.1e-28 PF01841: Transglut_core" amino acids 129 to 246 (118 residues), 55.6 bits, see alignment E=8.8e-19 PF09899: DUF2126" amino acids 276 to 1167 (892 residues), 1340.9 bits, see alignment E=0

Best Hits

Predicted SEED Role

"Large protein containing transglutaminase-like domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1168 amino acids)

>GFF5553 Large protein containing transglutaminase-like domain (Hydrogenophaga sp. GW460-11-11-14-LB1)
MAIHVALSHITHYRYDRLVKLGPQVVRLRPAPHSRTKVLSYSQRIEPGEHFINWQQDPFA
NYQARLVFPEPTTEFKVTIDLVVEMAVYNPFDFFLEPSAENFPFKYDQAQQQELAPYLAT
APLTPLLKTYVDAVDRSERRTIDFLVEINQRLQHDIAYTIRMEPGVQTPEDTLKLKSGSC
RDSGWLLVQILRHMGLAARFVSGYLIQLTSDVKSVDGPNGPEKDFTDLHAWCEVFLPGAG
WIGLDPTSGLLAGEGHVPLACTPQPSSAAPVEGGVDKCEVEFSHHMSVTRIYESPRVTLP
YTDEQWAGVLALGEQVDADLEKHDVRLTMGGEPTYVATSDRDAAEWNTDALGPTKRGYAT
ELLGRLRAEYGAGGFVHMGQGKWYPGEQLPRWALSMFWRADGETLWHNPALLADERDDAQ
YTSDDARRFTQALARKLGLSTQYITPGYEDTWYYLWRERRLPVNVDPFDSKLDDELERAR
LRRVFSQGLDATVGYVLPLQASGRNGTLSNNGKSGYPRISGTVWSTGPWFFRDERMYLIP
GDSPMGYRLPLDSLPWVSAGDYPYHIEQDPHSARDPLPRGAAVKHQVSPHQVGGGFAEGG
TVSMQGMDFDPDAETVEGLRPGQPAPGSAPAQALAAKFPQRGESAAWLTRTALCVEARDP
HRSNGPKAEKAGGGKTQHLYIFMPPMALLEDYLDLLAAVEATAEKLGMRIVLEGYPPPRD
PRLKMLQVTPDPGVIEVNIHPAHNWGELVEHTEFLYEAAHQTRLCAEKFMTDGRHTGTGG
GNHFVLGGATPSDSPFLRRPELLGSLLAYWHNHPSLSYLFSGLFIGPTSQAPRVDEARND
QLYELEIALAQIGQNRQTYGEDMPPWMVDRTLRNILIDVTGNTHRSEFCIDKLYSPDGPT
GRLGLLELRAFEMPPHARMSIAQQLLLRAMIARFWKQPWQGRLTRWGTELHDRCLLPTFV
RMDFEDVLTDMADAGYAFDMAWFEPHFEFRFPLVGEVAARGIELTIRSALEPWHVMGEEG
AVGGTVRYVDSSLERVEVRVSGFNDSRHVITCNGRALPLQSTGTAGEYVAGVRYKAWSPP
SALHPSIAAHAPLTFDIVDTWLQRSMGGCQYHVAHPGGRNYDTFPVNAYEAESRRLSRFF
QMGHTPGRMDVTPAQHSREFPFTLDLRT