Protein Info for GFF550 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 44 to 61 (18 residues), see Phobius details amino acids 91 to 108 (18 residues), see Phobius details amino acids 114 to 132 (19 residues), see Phobius details amino acids 137 to 156 (20 residues), see Phobius details amino acids 162 to 184 (23 residues), see Phobius details amino acids 193 to 210 (18 residues), see Phobius details amino acids 262 to 280 (19 residues), see Phobius details amino acids 313 to 333 (21 residues), see Phobius details amino acids 348 to 373 (26 residues), see Phobius details amino acids 385 to 402 (18 residues), see Phobius details PF11862: DUF3382" amino acids 6 to 103 (98 residues), 88.2 bits, see alignment E=3.5e-29 PF02653: BPD_transp_2" amino acids 112 to 398 (287 residues), 216.7 bits, see alignment E=3.4e-68

Best Hits

Swiss-Prot: 100% identical to LIVM_SALTY: High-affinity branched-chain amino acid transport system permease protein LivM (livM) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K01998, branched-chain amino acid transport system permease protein (inferred from 100% identity to sec:SC3491)

MetaCyc: 95% identical to branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM (Escherichia coli K-12 substr. MG1655)
ABC-15-RXN [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]; 7.4.2.2 [EC: 7.4.2.2]

Predicted SEED Role

"Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (425 amino acids)

>GFF550 Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MKPMHIAMALFSAAMFFVLAGVFMGVQLELDGTKLVVDTAADIRWQWIFIGTAVVFFFQL
LRPMFQKAVKHVSGPKFILPAIDGSTVKQKLFLMALLVIAVAWPFMVSRGSVDIATMTMI
YIILGLGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYYGLGFWTCLPLAGLVSAAAGF
LLGFPVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGGPNGISQIPKPTLFGLEFSRSTR
EGGWDTFSNFFGVKYDPSDRVIFLYLVALLLVVLSLFVINRLLRMPLGRAWEALREDEIA
CRSLGLSPTRIKLTAFTISAAFAGFAGTLFAARQGFVSPESFTFAESAFVLAIVVLGGMG
SQFAVILAAVLLVVSRELMRDFNEYSMLMLGGLMVLMMIWRPQGLLPMTRPQLKLKSGQA
KGEQA