Protein Info for GFF5484 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: DedA protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 217 transmembrane" amino acids 27 to 49 (23 residues), see Phobius details amino acids 55 to 82 (28 residues), see Phobius details amino acids 123 to 145 (23 residues), see Phobius details amino acids 156 to 176 (21 residues), see Phobius details amino acids 188 to 206 (19 residues), see Phobius details PF09335: VTT_dom" amino acids 49 to 174 (126 residues), 74.8 bits, see alignment E=4.4e-25

Best Hits

Swiss-Prot: 55% identical to DEDA_ECOLI: Protein DedA (dedA) from Escherichia coli (strain K12)

KEGG orthology group: K03975, membrane-associated protein (inferred from 80% identity to mpt:Mpe_A2029)

Predicted SEED Role

"DedA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (217 amino acids)

>GFF5484 DedA protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MEIVTFLIDFILNVDQHLQTFVQNYGAWVYALLFLIIFTETGVVVMPFLPGDSLLFVVGA
LCGVGLMSLPLAMVLLVIAAVLGDQTNYTIGRYFGPKVFQWENSRLFNRNAFNQAHAFYE
KYGGITIILARFMPFIRTFAPFVAGVAEMTRVKFTAYNVIGALIWVVGLTTAGYLFGNLP
WVQENLSMIIWALIIVPGLIAVFGAWKASREAKRNPA