Protein Info for GFF547 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Tyrosine recombinase XerC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 PF02899: Phage_int_SAM_1" amino acids 22 to 104 (83 residues), 47.3 bits, see alignment E=2e-16 PF00589: Phage_integrase" amino acids 135 to 305 (171 residues), 134.7 bits, see alignment E=3.1e-43

Best Hits

Swiss-Prot: 51% identical to XERC_RALPJ: Tyrosine recombinase XerC (xerC) from Ralstonia pickettii (strain 12J)

KEGG orthology group: K03733, integrase/recombinase XerC (inferred from 76% identity to pol:Bpro_1060)

Predicted SEED Role

"Tyrosine recombinase XerC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (343 amino acids)

>GFF547 Tyrosine recombinase XerC (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSPPERILAAPTGALGDDAALVQAYLNHVRVEKRLADRTVILYTLDLERLTAHARETGVG
LKAVQNAHIRRWIAQMHGAGRSARGIALILSGWRGFYVWLGRQGLIDHNPVQDVRAPKAG
KPLPKALGVDDAVQLASHHEASDDPALEARDACIAELLYGCGLRIGELVGLDVAASGQAR
GWIDAQDGEAHVLGKGSKRRSVPVGRQALAALAAWLVQRTAWAGEDPALFIGSRGQRLTP
QHIRVRLKRRSLLAGLSTPVHPHMLRHSFASHVLQSSGDLRAVQELLGHASISTTQVYTR
LDFQHLAQVYDAAHPRAGSRAGQAPEPLEGQPVTPTPRPPRSR