Protein Info for PS417_02775 in Pseudomonas simiae WCS417

Annotation: heat-shock protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 422 PF00012: HSP70" amino acids 10 to 230 (221 residues), 59.5 bits, see alignment E=2e-20 amino acids 299 to 395 (97 residues), 43.7 bits, see alignment E=1.2e-15

Best Hits

KEGG orthology group: K04046, hypothetical chaperone protein (inferred from 99% identity to pfs:PFLU0574)

Predicted SEED Role

"Putative heat shock protein YegD" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U439 at UniProt or InterPro

Protein Sequence (422 amino acids)

>PS417_02775 heat-shock protein (Pseudomonas simiae WCS417)
MKNPSPARACGIDFGTSNSTVGWIRPGEETLIALEDDKITLPSVVFFNFEERRPVYGRLA
LHEYLENYEGRLMRSLKSLLGSKLIKHDTSVLGTAMPFTDLLALFIGQLKSRAEANAGRE
FEEVVLGRPVFFVDDDPMADQEAENTLVDVARKIGFKDISFQYEPIAAAFDYESTIQKEE
LVLIVDIGGGTSDFSLVRLSPDRRHNDNRQSDILATGGVHIGGTDFDKQLSLNGMMPLFG
YGSRMKSGAYMPTSHHMNLATWHTINSVYSQKSQLALGSMRYDIEDTGGIDRLFKLIEQR
AGHWLAMEVEETKIQLTHEDSRHVLLDRVEPGLSVELSRALFESAIDGLLERVRNSVTQL
LNDASVSVAQVDTVFFTGGSSGIPALRHSISAMLPNARHVEGNIFGSIGSGLAIEASKRY
GC