Protein Info for GFF5424 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: two-component system sensor kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 618 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 181 to 202 (22 residues), see Phobius details amino acids 218 to 238 (21 residues), see Phobius details amino acids 246 to 271 (26 residues), see Phobius details amino acids 283 to 303 (21 residues), see Phobius details amino acids 311 to 332 (22 residues), see Phobius details amino acids 341 to 359 (19 residues), see Phobius details amino acids 371 to 388 (18 residues), see Phobius details PF07730: HisKA_3" amino acids 435 to 481 (47 residues), 26 bits, see alignment 1.1e-09

Best Hits

KEGG orthology group: None (inferred from 61% identity to rfr:Rfer_3372)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (618 amino acids)

>GFF5424 two-component system sensor kinase (Hydrogenophaga sp. GW460-11-11-14-LB1)
MTERIGWRWLVCLCLALGLTGSLHADDEEAPHRPALELREAQATVVVDGQTEQRQLTLPY
HWDRHNPGRAGRATFDLSFTLPEEPLGPWGIYLPRLGNAYEVWLNDMLVQHEGDMQQGNG
ADYAQVPRLVPLPAGLLERNNTLKVRVRADVGRRGGLSTVWIGPRESVAAKYAESYRWRV
TGSMIVVGFSLIVGLISLSLWVTQPDLSNTARQQRDPLYLYAGLAELFWAVRVGDALIEN
PVLPWPWWGVVPVVALAVWSWSMGLFCMNVARWENRPAGRLMANWLMALMLVSGPMAIWA
LGFGHPLALTTWYAALGLTFLVFGAVFLGLALRGASVPHRVVALAVLLNVAVGARDLYVF
RINPTYADSTLMRYSSVVFGLGLVYIVIERFRRVSAQARDLLNNLAARVSEKERELATTY
QRVEQLAREQERTAERTRILRDMHDGVGAHISSAIRQLESGRSSQQELLQTLRDSLDQLK
LSIDAMNLPPGDVTALLANLRYRLEPRLQASDIALRWAVELIEPLQRLDAGAMRQLQFMV
FEALSNVLQHAQATELSIEAVAAGQGVRLRIVDNGRGFDATVAWRKGLLAMRERARAIGA
VLSLQSAPGRTVVEIQLR