Protein Info for GFF5412 in Sphingobium sp. HT1-2

Annotation: Oxidoreductase, aldo/keto reductase family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF00248: Aldo_ket_red" amino acids 18 to 307 (290 residues), 230.4 bits, see alignment E=1.2e-72

Best Hits

KEGG orthology group: None (inferred from 60% identity to lch:Lcho_3695)

Predicted SEED Role

"Aldo-keto reductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (337 amino acids)

>GFF5412 Oxidoreductase, aldo/keto reductase family (Sphingobium sp. HT1-2)
MTTALPTRRLGALTVSAIGLGCMNLSHAYLPRPSANEAERLLRHALDAGVTFFDTAALYG
FGANEELLGRTIMDRRADFTLASKCVLAEIDGKRGLDGSPQAITRVLEDSLRRLRTDHID
LYYLHRLDPKVPIEESVGALVRGVEEGKIGAMGLSEMSAATIRRAHAVHPITAVQTEYSP
WSRNPEVAVLDACAELDIGFVAFSPVGRGLLAGGVGPQGVPEGDIRGAMPRFQPPHLAHN
LVLATKLNGLADEAGCTMAQLCLAWLLSRRDFIVPIPGTTNMAHLDEDLAAARLDLPRPL
LDRVDSLFDFRAVSGPRYPRDAQAQIDTELWEGEPLA