Protein Info for PS417_27320 in Pseudomonas simiae WCS417

Annotation: hemolysin secretion protein D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF16576: HlyD_D23" amino acids 47 to 265 (219 residues), 36.3 bits, see alignment E=5.6e-13 PF13533: Biotin_lipoyl_2" amino acids 51 to 97 (47 residues), 50.5 bits, see alignment 2.1e-17 PF13437: HlyD_3" amino acids 189 to 304 (116 residues), 44.3 bits, see alignment E=3.9e-15

Best Hits

KEGG orthology group: K01993, HlyD family secretion protein (inferred from 96% identity to pfs:PFLU5888)

Predicted SEED Role

"HlyD family secretion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UTP9 at UniProt or InterPro

Protein Sequence (321 amino acids)

>PS417_27320 hemolysin secretion protein D (Pseudomonas simiae WCS417)
MSTNHHTSRLFAIALIGLLLGAGGFGYWRSTQDRLPEGLSMGNGRLESTEVQIAAKIPGR
LAEVRVDEGDKVLKGQLLARMDTRTLEAQRAQAEAEVLRAKENFAAAEANVQLRQSEQLL
ANQELRRTQELYKRGFASSQLIDQQQARQNTGNAAVVAAQAQVASVKAAIGAAQAQVAQL
TSEIDDSSLRAPIDGIIQLRLAEPGEVLGAGGRVLLLIDPNDQYMNLYLPASVTGRLTVG
SDARILLDALPDQPLPAKISFVAAKSQFTPKEVETRDERQKLVFRVKLRLTQPSAVPQAK
PGMPGAGYVRTADIDWPANLR