Protein Info for PS417_27210 in Pseudomonas simiae WCS417

Annotation: AsnC family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 156 PF13404: HTH_AsnC-type" amino acids 5 to 46 (42 residues), 67.8 bits, see alignment E=1.1e-22 PF13412: HTH_24" amino acids 5 to 52 (48 residues), 71.4 bits, see alignment E=7.4e-24 PF08279: HTH_11" amino acids 10 to 50 (41 residues), 23.5 bits, see alignment E=8.6e-09 PF01037: AsnC_trans_reg" amino acids 72 to 145 (74 residues), 71.3 bits, see alignment E=1e-23

Best Hits

Swiss-Prot: 40% identical to DECR_ECO57: DNA-binding transcriptional activator DecR (decR) from Escherichia coli O157:H7

KEGG orthology group: K05800, Lrp/AsnC family transcriptional regulator (inferred from 99% identity to pfs:PFLU5865)

Predicted SEED Role

"Transcriptional regulator, AsnC family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UMM2 at UniProt or InterPro

Protein Sequence (156 amino acids)

>PS417_27210 AsnC family transcriptional regulator (Pseudomonas simiae WCS417)
MHSELDAYDRRILALLQEDASLSSAQIAEQVGLSQSPCWRRIQRLKEEGVIRGQVTLLDR
KKIGLNTQIFAEVKLNAHGRSNFTEFTDAIRGFPEVLECYVLMGAVDFLLRIVTSDIEAY
ERFFFEKLSMVPGIQEVNSIVALSEIKSTTSLPVLR