Protein Info for GFF5313 in Variovorax sp. SCN45

Annotation: Protein-methionine-sulfoxide reductase catalytic subunit MsrP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 341 transmembrane" amino acids 39 to 57 (19 residues), see Phobius details PF00174: Oxidored_molyb" amino acids 119 to 274 (156 residues), 118.7 bits, see alignment E=1e-38

Best Hits

Swiss-Prot: 65% identical to MSRP_RALSO: Protein-methionine-sulfoxide reductase catalytic subunit MsrP (msrP) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K07147, (no description) (inferred from 87% identity to vpe:Varpa_1220)

Predicted SEED Role

"Putative sulfite oxidase subunit YedY"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (341 amino acids)

>GFF5313 Protein-methionine-sulfoxide reductase catalytic subunit MsrP (Variovorax sp. SCN45)
MSFHSRPLRRHSSSDDNGFIHPVPSEITSRAAYESRREMLKLMAGGVAGAALAGFAARDA
WAQTARPNKLAALPGAKSAVPSAMSMDKLTDYKDASTYNNFYEFGTDKADPAKNAGTLKT
RPWTVEVEGLVKKPGKFGIEDLLKLSAQEERIYRLRCVEGWSMVIPWVGYSLAELIKKVE
PQGNAKFVEFVTLADPKTMPFVGSHVLDWPYTEGLRMDEAMHPLTLLAFGMYGEVLPNQN
GAPVRLVVPWKYGFKSAKSIVKIRFVEKEPSTAWNKAAANEYGFYSNVNPNVDHPRWSQA
TERRIGDGGGLFAKRRKTEMFNGYEAQVGQLYAGMDLKKNY