Protein Info for GFF5301 in Variovorax sp. SCN45

Annotation: ABC transporter, ATP-binding protein (cluster 1, maltose/g3p/polyamine/iron); ABC transporter, ATP-binding protein (cluster 10, nitrate/sulfonate/bicarbonate)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 272 PF00005: ABC_tran" amino acids 39 to 178 (140 residues), 114.4 bits, see alignment E=6.4e-37

Best Hits

Swiss-Prot: 47% identical to Y412_METJA: Uncharacterized ABC transporter ATP-binding protein MJ0412 (MJ0412) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K02049, sulfonate/nitrate/taurine transport system ATP-binding protein (inferred from 82% identity to bps:BPSL0037)

MetaCyc: 38% identical to taurine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-64-RXN [EC: 7.6.2.7]

Predicted SEED Role

"ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component" in subsystem Alkanesulfonate assimilation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (272 amino acids)

>GFF5301 ABC transporter, ATP-binding protein (cluster 1, maltose/g3p/polyamine/iron); ABC transporter, ATP-binding protein (cluster 10, nitrate/sulfonate/bicarbonate) (Variovorax sp. SCN45)
MRNGTPPSGGNGSAVTSAIDFNDVSLRFISQDGNATVALRNFSMSVARGEFVAIVGPTGC
GKSTTLNMITGLLKPTVGDVKVMGKPVTGVDPRIGFVFQADAVFPWRSVEDNVAAGPIFR
GKPKKEAMELAQEWIHRVGLAKFGKHYPHQLSGGMRKRVALAQTFINNPEILLMDEPFSA
LDMQTRTLMQDELLQLWSGNGGSVVFVTHDLEEAIALADRVFVLSARPATLKRVYEIDLP
RPRIMSEVRYDPQFIELSKRIWDDLREEVVIQ