Protein Info for GFF5280 in Variovorax sp. SCN45

Annotation: Transcriptional regulator of various polyols utilization, AraC family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 318 PF12833: HTH_18" amino acids 228 to 307 (80 residues), 88.2 bits, see alignment E=3.7e-29 PF00165: HTH_AraC" amino acids 274 to 306 (33 residues), 27.8 bits, see alignment 2.1e-10

Best Hits

KEGG orthology group: None (inferred from 96% identity to vpe:Varpa_1199)

Predicted SEED Role

"Transcriptional regulator of various polyols utilization, AraC family" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (318 amino acids)

>GFF5280 Transcriptional regulator of various polyols utilization, AraC family (Variovorax sp. SCN45)
MTTSTRKRSVPRQRQPELERDFARSPSLGYEAPEETGLVRCLAHGFPSPLVRWHFHEDYE
LHLITETSGKAFIGDWIGPFQPGHLVLCGPRLPHNWISLDVPEGGAAGRDRVIQFRHEPI
ESAAAGIPELREVMQLLERARHGIEFFGMSQQAQAHWDRIKAARGVRRLGLFLDFMADLA
QCTDYRLLSSVQMQGAQGADGDAQVDQINGIVNRITNNMADPISMSDVAAELGMSESRFS
RFFRRSTGNSFTDFVNRVRINSACHLLMQTDHYVTDICYQVGFNNVANFNRRFLEIKGMT
PSEFRRQADTRFGGGISS