Protein Info for GFF524 in Variovorax sp. SCN45

Annotation: Tripartite tricarboxylate transporter TctB family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 178 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 52 to 70 (19 residues), see Phobius details amino acids 94 to 123 (30 residues), see Phobius details amino acids 144 to 167 (24 residues), see Phobius details PF07331: TctB" amino acids 21 to 170 (150 residues), 78 bits, see alignment E=4.2e-26

Best Hits

KEGG orthology group: K07794, putative tricarboxylic transport membrane protein (inferred from 87% identity to vpe:Varpa_3454)

Predicted SEED Role

"Tricarboxylate transport protein TctB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (178 amino acids)

>GFF524 Tripartite tricarboxylate transporter TctB family (Variovorax sp. SCN45)
MTTPDSSAPPQPAATWPQTLVGAGVLLTGLALAFGAIGISSEAGYGGVGPNFLPWLVSVV
LVLCGGWIVWEARTGGFRELDAPSGADHAYWPGFVWVSAGLLLNAALITTLGFILSCTLC
YVLAVQGLRRASGQGGVNSPRTWLTDFIAGLCISAPVFWTFTQFLAINLPGLTSTGWL