Protein Info for GFF5228 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Transcriptional regulator, TetR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 226 PF00440: TetR_N" amino acids 34 to 80 (47 residues), 49.1 bits, see alignment 4e-17 PF17938: TetR_C_29" amino acids 102 to 220 (119 residues), 159.4 bits, see alignment E=4e-51

Best Hits

Swiss-Prot: 32% identical to NICS_PSEPK: HTH-type transcriptional repressor NicS (nicS) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: None (inferred from 74% identity to lch:Lcho_0413)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

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Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (226 amino acids)

>GFF5228 Transcriptional regulator, TetR family (Hydrogenophaga sp. GW460-11-11-14-LB1)
MNETVHSRRRAARSAAPVKETTRTNDPERTMANIMEVALAEFAEKGLAGARIDEIAAATQ
TSKRMIYYYFQSKEGLYLAALEESYRRMREIESQQHLEDLEPVAALRKLVEFTFDHHASN
ENYIRLVISENMNRGQFLAQSHSIQQLNVPAISAIRQLYERGVASGVFRPGLDAIDIHAS
ISALTFFNVSNRHTFGLIFKRDLTDPKVAAARRTAITEMVLRYVRA