Protein Info for GFF520 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Glutamate Aspartate transport system permease protein GltJ (TC 3.A.1.3.4)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 251 transmembrane" amino acids 38 to 62 (25 residues), see Phobius details amino acids 80 to 98 (19 residues), see Phobius details amino acids 108 to 127 (20 residues), see Phobius details amino acids 147 to 169 (23 residues), see Phobius details amino acids 181 to 199 (19 residues), see Phobius details amino acids 211 to 232 (22 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 34 to 132 (99 residues), 64.3 bits, see alignment E=5.9e-22 PF00528: BPD_transp_1" amino acids 54 to 238 (185 residues), 46.7 bits, see alignment E=1.6e-16

Best Hits

KEGG orthology group: K10003, glutamate/aspartate transport system permease protein (inferred from 85% identity to adn:Alide_0695)

Predicted SEED Role

"Glutamate Aspartate transport system permease protein GltJ (TC 3.A.1.3.4)" (TC 3.A.1.3.4)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (251 amino acids)

>GFF520 Glutamate Aspartate transport system permease protein GltJ (TC 3.A.1.3.4) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSWDWQVFCEDTIERQPVESCFGKGGDITYLDWMLSAWGWTVSVSLLALLLALVLGIVIG
TLRTLPDRPMVVRLGNAWVELFRNIPLLVQIFLWYHVVPTMFPAMREVPGFVLVVFALGF
FTSARIAEQVRSGIQALPRGQRYAGMAMGFTTFQYYRYVLLPMAFRIIIPPLTSETMNIF
KNSSVAFAVSVSELTMFAMQAQEETSRGIEVYLAVTGLYIISAFAINRIMAFIEKRARIP
GFVVAGGTGGH