Protein Info for GFF5198 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 184 PF00989: PAS" amino acids 4 to 101 (98 residues), 33 bits, see alignment E=1.1e-11 TIGR00229: PAS domain S-box protein" amino acids 5 to 124 (120 residues), 39.6 bits, see alignment E=2.7e-14 PF13426: PAS_9" amino acids 21 to 118 (98 residues), 32.9 bits, see alignment E=1.3e-11 PF00196: GerE" amino acids 127 to 178 (52 residues), 58.7 bits, see alignment E=7.1e-20

Best Hits

KEGG orthology group: None (inferred from 76% identity to pol:Bpro_1904)

Predicted SEED Role

"Response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (184 amino acids)

>GFF5198 Response regulator (Hydrogenophaga sp. GW460-11-11-14-LB1)
MEIDYRLAFDLAPVGLALSRQRIMVDCNQVLCEMFGATREQLVGQSFQILYPSADEYERI
GERMAPLLGRSGTYADNRIMKRVSGPQQGETFWCHVTGRALQRAAPHAAGIWSFEDLSAS
RTVKAELTPREREVAAFLMDGMTSKQIGKALAISHRTVEIYRARLMRKYQAHSTPDLMQR
LLAG