Protein Info for GFF5197 in Variovorax sp. SCN45

Annotation: Galactofuranose ABC transporter, ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 504 PF00005: ABC_tran" amino acids 23 to 176 (154 residues), 108.5 bits, see alignment E=4.4e-35 amino acids 281 to 434 (154 residues), 88.1 bits, see alignment E=9e-29

Best Hits

Swiss-Prot: 43% identical to RGMG1_BURL3: Putative ribose/galactose/methyl galactoside import ATP-binding protein 1 (Bcep18194_B0624) from Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)

KEGG orthology group: K02056, simple sugar transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 94% identity to vap:Vapar_1048)

Predicted SEED Role

"Predicted L-arabinose ABC transport system, ATP-binding protein" in subsystem L-Arabinose utilization

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (504 amino acids)

>GFF5197 Galactofuranose ABC transporter, ATP-binding protein (Variovorax sp. SCN45)
MADDQPVLALKGIHKQFGGIPVLRDVQLRLYAGEIHALMGQNGAGKSTLIKVLTGVLPSS
GGEMLLDGQPIRPASPLEAQKLGISTVYQEVNLCPNLSVAENVFAGRYPRCGVAQGFRID
WAGVNRRAEELLARIGLDIDVTRLLSSYSVAVQQMVAIARALGVSSKVLILDEPTSSLDD
DEVEKLFEVLRRLRGEGLAIVFVTHFLNQMYAVSDRITVLRNGGWIGEWKAAELGPQALI
AAMLGRELAAQSARPAALPAFDEAAPALLQAEGLGQAGQLQATDLRVRAGEVVGIAGLLG
AGRTELARLLFGLETPDRGVLKVDGRSVSFSNPADAIREGLALCPEERKTDGIVSELSVR
ENIALALQARLGTKRFLSHAEQTEMAQRFVKSLGIKTASVETPIGLLSGGNQQKAMIARW
LATEPRVLILDEPTRGIDVAAKQEIMEEILRLAKAGMAVIFISSEMSEVVRVAHRIVVLR
DRKKVGELPGGATEDEVYEMIAAT