Protein Info for GFF5163 in Variovorax sp. SCN45

Annotation: Soluble lytic murein transglycosylase (EC 4.2.2.n1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 676 signal peptide" amino acids 1 to 41 (41 residues), see Phobius details PF01464: SLT" amino acids 507 to 611 (105 residues), 89.9 bits, see alignment E=4.5e-30

Best Hits

KEGG orthology group: K08309, soluble lytic murein transglycosylase [EC: 3.2.1.-] (inferred from 89% identity to vap:Vapar_0992)

Predicted SEED Role

"Soluble lytic murein transglycosylase precursor (EC 3.2.1.-)" (EC 3.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (676 amino acids)

>GFF5163 Soluble lytic murein transglycosylase (EC 4.2.2.n1) (Variovorax sp. SCN45)
MQFPSILASKRRRPRSAPPALVFSAVLALAALLSQQPAAAQNNTNDDVLIQMKQAFQRGD
KARLSALLPQARGHALEPWAAYWELKARLSEASPNEVQDFFARYAGTYQEDRLRNDWLLL
TGQRRDWDNFSASIAGFRMGDDAQVRCYATLVDTLRSGTATQAQADEVRRNWFAQKDADD
GCLTASDRMVAARLMTPADAWKKARLAMEANRPQAARGAVTIAAPDALPLFEELNASSAK
FLTGRAFVAAKSRKELVVLALIKVAIADPDLAASQLDSKWGPMLSAEERNWLWGTIGRQA
AGKLSPQAGGYFANVTKNSDLSDDMLGWRVRAALRAGQWKEVAPAINAMSESAQLDPTWV
YWKARALANNGSEERRAQARELYQSIAGSRGFYEMLALEELGQRTVVPTRPAPLTPEEKA
TARANPSLARGLYAIAIGLRPEGTREWNYATNLHDKGGMDDRALLAAADFACQREVWDRC
INTSERTKGVVDVDQRFPMPFHDTVLRKSQDIGLDPAYVYGLIRQESRFIMDARSGVGAS
GLMQVMPATARWTARKIGLTDFSPNQINDRETNITIGTNYLKLALDDFDGSMALAAAAYN
AGPGRPRNWRNGPVIDAAIWAENVPFSETRDYVKKVLANTTNYAAIISGRPQSLKERLGR
VGPRDAAEPEPNKDLP