Protein Info for GFF5132 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 152 PF01479: S4" amino acids 12 to 57 (46 residues), 49.1 bits, see alignment E=1.8e-17

Best Hits

Swiss-Prot: 49% identical to HSLR_AERSA: Heat shock protein 15 homolog (hslR) from Aeromonas salmonicida

KEGG orthology group: K04762, ribosome-associated heat shock protein Hsp15 (inferred from 61% identity to rfr:Rfer_2640)

Predicted SEED Role

"Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)" in subsystem Heat shock dnaK gene cluster extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (152 amino acids)

>GFF5132 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MKPAPDPASDKVRLDKWLWAARFYKTRGLSSEAIDKGHVRLNGLPVKPSRDVKPGDTLEL
RIGPDTRTVIVKGLSGVRGPAPVAALLYEETAASLKLRSEAAERRRLAPEPAHSQPMGRP
TKRDRRQIEDLRDAPPRGEWNERWSASLDDEE