Protein Info for GFF5098 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Sulfate transport system permease protein CysW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 transmembrane" amino acids 20 to 44 (25 residues), see Phobius details amino acids 67 to 94 (28 residues), see Phobius details amino acids 106 to 132 (27 residues), see Phobius details amino acids 144 to 164 (21 residues), see Phobius details amino acids 205 to 228 (24 residues), see Phobius details amino acids 250 to 270 (21 residues), see Phobius details TIGR00969: sulfate ABC transporter, permease protein" amino acids 17 to 276 (260 residues), 343.4 bits, see alignment E=9.7e-107 TIGR02140: sulfate ABC transporter, permease protein CysW" amino acids 20 to 279 (260 residues), 435.8 bits, see alignment E=5.9e-135 PF00528: BPD_transp_1" amino acids 84 to 270 (187 residues), 49.7 bits, see alignment E=1.9e-17

Best Hits

Swiss-Prot: 53% identical to CYSW_ECOLI: Sulfate transport system permease protein CysW (cysW) from Escherichia coli (strain K12)

KEGG orthology group: K02047, sulfate transport system permease protein (inferred from 88% identity to vap:Vapar_2959)

MetaCyc: 53% identical to sulfate/thiosulfate ABC transporter inner membrane subunit CysW (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate transport system permease protein CysW" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (305 amino acids)

>GFF5098 Sulfate transport system permease protein CysW (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSTATSPRTARKGTTEAAWVRYTLIGVALLFMALFLVLPLAAVFTEALRKGFDAYWEALK
DPDAWSAIRLTLLTAAIAVPLNLVFGVAAAWAVAKYEFRGKSFLTTLIDLPFSVSPVVAG
LIYVLVFGAQGWLGPWLSEHDIKIVFAVPGIILATIFVTFPFIARELIPLMQAQGNDEEQ
AAIVLGASGWQTFWHVTLPNIKWGLIYGVILCNARAMGEFGAVSVVSGHIRGQTNTMPLH
VEILYNEYQSVAAFAVASLLALLALVTLVIKSVAEWQMERELKALAELPPERPTPANPTL
LGQTP