Protein Info for GFF5029 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Alkanesulfonates-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 344 transmembrane" amino acids 26 to 46 (21 residues), see Phobius details PF04069: OpuAC" amino acids 57 to 261 (205 residues), 36.6 bits, see alignment E=1e-12 TIGR01728: ABC transporter, substrate-binding protein, aliphatic sulfonates family" amino acids 58 to 339 (282 residues), 246 bits, see alignment E=2.3e-77 PF13379: NMT1_2" amino acids 60 to 282 (223 residues), 44.4 bits, see alignment E=4.7e-15 PF00497: SBP_bac_3" amino acids 98 to 230 (133 residues), 27.5 bits, see alignment E=5.4e-10 PF12974: Phosphonate-bd" amino acids 98 to 199 (102 residues), 33.6 bits, see alignment E=7.5e-12 PF09084: NMT1" amino acids 107 to 262 (156 residues), 47.8 bits, see alignment E=4.3e-16

Best Hits

KEGG orthology group: None (inferred from 75% identity to pna:Pnap_2420)

Predicted SEED Role

"Alkanesulfonates-binding protein" in subsystem Alkanesulfonate assimilation or Alkanesulfonates Utilization or Putative sulfate assimilation cluster

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (344 amino acids)

>GFF5029 Alkanesulfonates-binding protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MSELFQHHPEAGVPVEPSRSSRLKQWAIGFLVFVIAAFGLALLLLPVPEAKAQTRGELRI
GYQKSASLFVLQKAQGTLEKKLSPLGFGVKWVEFPAGPQLLEGLNVGAVDVGYVGEAPPI
FAQAAGAQFVYFGYDPAAPRAEAILVTKDSPIKSVADLKGKKVALNKGSNVHYLLVKQLE
KHGLKITDITPVYLAPADGRAAFESKNVDAWVIWDPFQAAAEKATGARVLADGTGGVVNN
YQYYLGARNFVSKNPKVIEALFEDSVSQGIWLKKNLRQAAELIAPLQGLPVEVVELALQR
YEFNVKPITPAVAADQQKIADTFFELKLIPKAIKVNEAVVVAQP