Protein Info for GFF5012 in Variovorax sp. SCN45

Annotation: Citronellol dehydrogenase; Citronellal dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 transmembrane" amino acids 237 to 254 (18 residues), see Phobius details PF00106: adh_short" amino acids 20 to 205 (186 residues), 166.5 bits, see alignment E=8.1e-53 PF08659: KR" amino acids 22 to 136 (115 residues), 44.2 bits, see alignment E=3.2e-15 PF13561: adh_short_C2" amino acids 29 to 258 (230 residues), 170.9 bits, see alignment E=5.2e-54

Best Hits

Swiss-Prot: 34% identical to FABG_THEMA: 3-oxoacyl-[acyl-carrier-protein] reductase FabG (fabG) from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

KEGG orthology group: K13774, citronellol/citronellal dehydrogenase (inferred from 91% identity to vpe:Varpa_0337)

Predicted SEED Role

"Citronellol and citronellal dehydrogenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (300 amino acids)

>GFF5012 Citronellol dehydrogenase; Citronellal dehydrogenase (Variovorax sp. SCN45)
MNASPASYRSVFAPGLFGGQVIVVTGGGSGIGRCTAHELASLGAQVVLVGRKPEKLEAVK
AEIEAAGGKAATQAFDIRQEEAVRDAVRAIVAAHGRIDGLVNNAGGQYITPLADISAKGW
EAVIHTNLTGGFLVARECFVQSMQANGGAIVNIVADMWGSMPNMGHSGAARAGMVSFTET
AALEWAASGVRVNAVAPGYIASSGMDHYPPEAGDMLRAMRKTVPAGRFGNEAETSAAIAF
LLSPAASFISGSVLRVDGARPQVRMGWPMALPDAQARQRPAVKPFDGFHLAQTPRVFQEK