Protein Info for GFF50 in Sphingobium sp. HT1-2

Annotation: Phosphoglucomutase (EC 5.4.2.2)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02878: PGM_PMM_I
  • amino acids 13 to 152 (140 residues), 108.5 bits, E=4.6e-35
• PF02879: PGM_PMM_II
  • amino acids 184 to 285 (102 residues), 43.9 bits, E=5.9e-15
• PF02880: PGM_PMM_III
  • amino acids 294 to 406 (113 residues), 92.5 bits, E=3.9e-30
• PF24947: PGM1_C_vert_fung
  • amino acids 408 to 539 (132 residues), 151.9 bits, E=2.8e-48

Best Hits

Swiss-Prot: 73% identical to PGM_RHIRD: Phosphoglucomutase (pgm) from Rhizobium radiobacter

KEGG orthology group: K01835, phosphoglucomutase [EC: 5.4.2.2] (inferred from 89% identity to sjp:SJA_C1-17850)

Predicted SEED Role

"Phosphoglucomutase (EC 5.4.2.2)" (EC 5.4.2.2)

MetaCyc Pathways

• O-antigen building blocks biosynthesis (E. coli) (10/11 steps found)
• dTDP-β-L-rhamnose biosynthesis (5/5 steps found)
• superpathway of anaerobic sucrose degradation (15/19 steps found)
• glycogen biosynthesis I (from ADP-D-Glucose) (4/4 steps found)
• glycogen degradation II (5/6 steps found)
• UDP-α-D-glucose biosynthesis (2/2 steps found)
• sucrose biosynthesis I (from photosynthesis) (7/9 steps found)
• glucose and glucose-1-phosphate degradation (4/5 steps found)
• sucrose degradation II (sucrose synthase) (4/5 steps found)
• glycogen degradation I (6/8 steps found)
• sucrose degradation IV (sucrose phosphorylase) (3/4 steps found)
• GDP-α-D-glucose biosynthesis (2/3 steps found)
• trehalose degradation V (2/3 steps found)
• superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis (4/6 steps found)
• D-galactose degradation I (Leloir pathway) (3/5 steps found)
• glucosylglycerol biosynthesis (3/5 steps found)
• sucrose biosynthesis II (5/8 steps found)
• starch degradation III (2/4 steps found)
• starch degradation V (2/4 steps found)
• colanic acid building blocks biosynthesis (7/11 steps found)
• starch biosynthesis (6/10 steps found)
• chitin biosynthesis (5/9 steps found)
• glycogen biosynthesis III (from α-maltose 1-phosphate) (4/8 steps found)
• CDP-6-deoxy-D-gulose biosynthesis (1/5 steps found)
• superpathway of dTDP-glucose-derived O-antigen building blocks biosynthesis (5/19 steps found)
• superpathway of mycolyl-arabinogalactan-peptidoglycan complex biosynthesis (13/33 steps found)
• streptomycin biosynthesis (1/18 steps found)

KEGG Metabolic Maps

• Galactose metabolism
• Glycolysis / Gluconeogenesis
• Nucleotide sugars metabolism
• Pentose phosphate pathway
• Starch and sucrose metabolism
• Streptomycin biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.2

Protein Sequence (542 amino acids)

>GFF50 Phosphoglucomutase (EC 5.4.2.2) (Sphingobium sp. HT1-2)
VIQTVATTPFDDQKPGTSGLRKKVRVFQQPHYAENFIQSVFDSLDGFAGQTLVIGGDGRY
LNREVIQIALRMAAANGFGRVLVGQGGILSTPAASHLIRSSGAFGGLVLSASHNPGGPDE
DFGIKYNVSNGGPAPEKVTDAIHARTLTIDSYRIIDAADVDIDTLGTSQLGAMTVEVVDP
VAGYAALMESLFDFPAIRAMIAGGFTLAFDSMSAVTGPYATEIFEKRLGAPAGTVMNGTP
LPDFGHHHPDPNLVHAKALYDRMMAADAPDFGAASDGDGDRNLIIGRHCYVTPSDSLAVL
AANAHLAPGYAGGLKGIARSMPTSGAADRVAQKLGIPLYETPTGWKFFGNLLDAGMATIC
GEESAGTGSDHVREKDGIWAVLLWLNILAARQQSVADIMADHWATYGRNYYARHDYEAIA
KDKADALMAALRDTLASLPGTGNSGGTVKAADDFAYTDPTDQSVSRNQGVRILFEDGSRV
VFRLSGTGTEGATLRVYIERYVGPDGDLALATGDALAPLVAAAQELADISGYTGMDQPSV
IT